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You will see your text:
Dopamine-immunoreactive axons in the brain of Aplysia.
The existence of a large dopaminergic system in the cerebral ganglia and central nervous system (CNS) of Aplysia has been proposed from previous studies. However, the cellular localization of this system has not been well established. Therefore, we injected the primary dopaminergic cell body product, tyrosine hydroxylase (TH), into the cerebral ganglia to determine the cellular localization of the dopaminergic system in Aplysia. A dual-labeling technique was used to visualize both the TH- and dopamine (DA)-immunoreactive (IR) systems in the same tissue. We used both light and electron microscopy, which demonstrated TH- and DA-IR axons and terminals in the perikarya, dendrites, and neuropils of the cerebral and pleural ganglia. The synaptic localization of the TH- and DA-IR axons and terminals was also demonstrated. These results indicate that the dopaminergic system of Aplysia is a well-developed and organized system, and they also establish the cellular localization of the TH- and DA-IR axons and terminals in Aplysia.. 2011). This
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